Antidotes Toxnet HDSB Erowid MykoWeb Snakebites Lidocaine Toxicity Hemodialysis in Toxicology Anticholinergic poisoning Cholinergic Poisoning Sympathomimetics Rumack Matthew Nomogram Used between 4 - 24 hours post ingestion cannot be used for ingestions > 24 hours ago or for chronic ingestions Start NAC empirically if ingestion is > 8 hours or patient is pregnant (i.e. don’t wait for APAP level to begin therapy) Lipid Emulsion (Review) Bolus 1.5 mL/kg (lean body mass) intravenously over 1 min Continuous infusion at 0.25 mL/kg/min Repeat bolus 1-2x for persistent cardiovascular collapse Double the infusion rate to 0.5 mL/kg per minute if Hypotensive Continue infusion for at least 10 mins after attaining circulatory stability Recommended upper limit: approximately 10-12 mL/kg lipid emulsion over the first 30 mins

•Used between 4 - 24 hours post ingestion
•cannot be used for ingestions > 24 hours ago or for chronic ingestions
•Start NAC empirically if ingestion is > 8 hours or patient is pregnant (i.e. don’t wait for APAP level to begin therapy)

•Bolus 1.5 mL/kg (lean body mass) intravenously over 1 min
•Continuous infusion at 0.25 mL/kg/min
•Repeat bolus 1-2x for persistent cardiovascular collapse
•Double the infusion rate to 0.5 mL/kg per minute if Hypotensive
•Continue infusion for at least 10 mins after attaining circulatory stability
•Recommended upper limit: approximately 10-12 mL/kg lipid emulsion over the first 30 mins